CA 72-4 (Carbohydrate Antigen 72-4) is a glycoprotein found on the surface of various cells, particularly cancer cells. Under normal conditions, CA 72-4 levels in the blood are very low. However, when malignant tumors develop, its concentration can rise significantly.
The CA 72-4 test serves several purposes, including:
Supporting Stomach Cancer Diagnosis: Elevated CA 72-4 levels can be a sign of stomach cancer. However, this test alone is not enough for diagnosis and should be combined with other methods like endoscopy and biopsy.
Monitoring Treatment Effectiveness: If a patient is undergoing cancer treatment, the CA 72-4 test helps assess the effectiveness of surgery, chemotherapy, or radiation therapy. A decrease in CA 72-4 levels may indicate that the treatment is working.
Detecting Recurrence: After cancer treatment, periodic testing can help detect the risk of cancer recurrence early.
2. When Should You Get a CA 72-4 Test?
Doctors may recommend a CA 72-4 test in the following cases:
Patients experiencing symptoms suggestive of stomach cancer, such as abdominal pain, loss of appetite, or unexplained weight loss.
Monitoring during stomach cancer treatment.
Checking for cancer recurrence after treatment.
In some cases, it may be used for other cancers like ovarian, colorectal, or pancreatic cancer.
3. How is the CA 72-4 Test Performed?
The CA 72-4 test is a simple blood test that involves:
Blood Sample Collection: A healthcare professional draws a small amount of blood from a vein in the arm.
Laboratory Analysis: The sample is analyzed to measure CA 72-4 levels.
Receiving Results: Typically, test results are available within 1-2 days.
4. Understanding CA 72-4 Test Results
Normal: CA 72-4 levels are usually below 6 U/mL.
Mild Elevation: Could be due to conditions like gastritis, pancreatitis, or other benign diseases.
High Elevation: May indicate stomach cancer or other types of cancer.
It’s important to note that CA 72-4 is not a definitive diagnostic test for cancer. If results are elevated, additional tests are required for confirmation.
5. Factors That May Affect CA 72-4 Test Results
Several factors can influence CA 72-4 levels, including:
Benign conditions such as gastritis or pancreatitis.
Certain medications affecting the immune system.
Laboratory testing errors.
6. Is the CA 72-4 Test Accurate?
The CA 72-4 test has a certain level of sensitivity and specificity, but it is not 100% accurate. Some cancer patients may have normal CA 72-4 levels, while others may have elevated levels due to non-cancerous conditions. Therefore, this test should always be used alongside other diagnostic methods.
7. Conclusion
The CA 72-4 test is a useful tool for diagnosing and monitoring stomach cancer, but it should not replace other diagnostic methods. If your CA 72-4 levels are high, consult your doctor for further evaluation and additional tests.
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